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Water Quality knowledge on Biochemistry analyzer Usage

Hello, everyone,this is the clinical partner of the biochemical analyzer - pure water system!

Biochemical analyzers, often referred to as biochemistry analyzers, are instruments that use electro-optical colorimetry to measure certain chemical components in body fluids. Due to its fast measurement speed, high accuracy, and low consumption of reagents, it has been widely used in hospitals, epidemic prevention stations, and family planning service stations. Biochemical analyzers can greatly increase the efficiency and benefits of routine biochemical tests.


Biochemical Instrument Development History

First Generation


Ultraviolet light, visible light, infrared light, and laser light are used to determine the absorption spectrum of a substance, and the absorption spectrum is used to qualitatively and quantitatively analyze the substance and analyze the structure of the substance. This method is called spectrophotometry or spectrophotometry. The instrument used is called spectrophotometry. Photometer.






Second Generation

Semi-automatic biochemistry analyzer

A semi-automatic analyzer means that some of the operations in the analysis process (such as adding a sample, holding heat, inhalation color comparison, and result recording) need to be done manually, while the other part of the operation can be done automatically by the instrument. This type of instrument is characterized by its small size, simple structure, and high flexibility. It can be used separately, and can be used in conjunction with other instruments at a low price.


 Semi-automatic biochemistry analyzer



Third generation

Automatic analyzer

Automatic biochemical analyzer, the entire process from the sample to the output is completely completed by the instrument. The operator only needs to place the sample on the analyzer at a specific location. Select the program to start the instrument and wait for the inspection report.


Automatic analyzer



In fact, each clinically tested chemiluminescence system will be equipped with a pure water system. Since chemiluminescence is a concentrated reagent, it requires internal dilution of the instrument before it can be used for detection. At the same time, the instrument itself needs to be operated, maintained, and cleaned, and it also requires high quality. Qualified pure water. Therefore, the choice of pure water system has two most important factors: water quality and quantity.


Clinical use water analysis


Have you encountered the following situation?

❶ Whether the biochemical analyzer is normal, but the calibration of calcium and magnesium ions

❷ Do you doubt whether alkaline phosphatase exceeds the standard and all other biochemical indicators are normal?

❸ Do you question the stability of the myocardial index of the immunoassay analyzer?


Analysis of susceptibility to interference in clinical trials


Affected by mineral and organic biofilms


Affected by pellicles, detergents, minerals


Affected by impurities released from tap water treatment systems


By citrate, detergents, organics (humus and coal fulvic acid)


Affected by industrial waste water, organic matter, H2O2


Affected by citrate, organic matter


Affected by minerals, organic matter (humus and coal humic acid), detergents


Affected by citrate, mineral effects


Affected by plastics, chemicals


Affected by citrate, tap water treatment system

Troponin I

Affected by biofilm

Microorganisms and organic matter are also the main problems and challenges we face today!


When such a problem occurs, has it been considered that the effect of clinically used pure water?


Clinical laboratory reagent water CLRW 



 standard value





>10 MΩ·cm 

@25 °C




Analysis and monitoring


< 500 ppb

Organic matter



Or off-line monitoring


< 10 cfu/mL




Tablet counting


 < 1

With0.22 µm




Terminal filter membrane

Challenging experiment

Quality Assurance




Clinical laboratory accreditation



ISO 15189

Concept: The special requirements of the medical laboratory for quality and competence, ISO 15189 provides a framework that allows the medical laboratory to improve their workflow in line with the quality management system.

Benefits: The laboratory establishes its own testing quality and technology management system and guides the operation in various aspects. It provides important reference for assessing and recognizing the capabilities of medical laboratories, including technical capacity, professional services, and effective employee management. The standard helps to promote the general quality management of medical laboratories and control of all operating procedures from patient preparation and confirmation to collecting and testing samples.



Concept: The American Association of Pathologists (COLLEGE OF AMERICAN PATHOLOGISTS, CAP) is a non-profit clinical laboratory accreditation body in the United States. It has developed a detailed checklist for all aspects of clinical laboratory disciplines, and ensures the experiment through strict requirements. The room meets quality standards to improve the actual work of the laboratory.

Benefits: The CAP-certified laboratory represents the quality of its testing room to the highest level in the world


What do we need to do?



Create a complete instrumentation file

1 Marks, acceptance records, factory calibration certificates, instruction manuals, training records of manufacturers and instrument models

2 consumables quality certificate, calibration certificate

3 Use records, regular replacement supplies records, cleaning and maintenance records


Prepare pure water system

operating procedures

1 Quick Operation List

2 Operation Manual


Good water quality monitoring records and water records

1 Ion content monitoring

2 Organic content monitoring

3 Microbiological monitoring


Maintain and replace consumables on time and record

1 reverse osmosis disinfection and cleaning, it is recommended to clean every three months;

2 Replacement of consumables according to manufacturer's recommendations.


Make sure the instrument is operating normally

When the instrument alarms or prompts information, it should be processed in time


Calibrate the built-in instruments regularly and have traceability

1 Conductivity meter calibration

2 TOC calibration



Any question

Please feel free to contact us


Company Name:         Sichuan Zhuoyue Water Treatment Equipment Co.,ltd.

Address:                      No.799 Jinfu Road, Jinniu District, Chengdu City, Sichuan Province, China

Post code:                   610036

Tel :                              0086-28-86634818 

Fax:                              0086-28-87527995

Cell:                             0086 138 0819 7592

Email:                          monica@sczyscl.com

Website:                      https://zhuoyuescl.en.alibaba.com/